The Animal Replacement Centre of Excellence (The ARC) Queen Mary University of London (QMUL) - Professor Mike Philpott and Dr Adrian BiddleThe ARC will provide a unique environment for scientists to work together to develop human-based models of skin, breast and prostate cancer, replacing mouse models. It also aims to inspire the next generation of scientists through education about animal free research. The Animal Replacement Centre is a joint venture between the Blizard Institute at Queen Mary University of London (QMUL) and Animal Free Research UK. The ARC, funded by a £1 million investment by Animal Free Research UK, aims to maximise and build upon a long-standing successful partnership with the Blizard Institute, a pioneer in the development of in vitro human research models. The ARC will help provide a unique environment where a team of scientists will work together with the common goal to develop, validate and apply human-based models of disease. The research programme at The ARC will be led by Professor Mike Philpott and is supported by the DHT lecturer Dr Adrian Biddle. Initially the research will concentrate on skin, breast and prostate cancer and may develop, over the years, to incorporate other research fields with strong animal-replacement requirements. The ARC also aims to inspire the next generation of scientists through education and further funding opportunities. The Blizard Institute and QMUL have worldwide reputations for scientific and research excellence, and provide the perfect environment for interdisciplinary collaborative research - a key to success in replacing the use of animals in biomedical research. The ARC will serve as a focal point for innovative and cutting-edge technology development and extend QMUL’s portfolio of non-animal research. The success of this initiative could have global implications for the advancement of non-animal medical research.