Previous summer students
Supervised by Dr Yubing Shi at Northampton University, Zhuo Song used computer modelling to help replace sheep and pig experiments in the clinical study of artificial hearts.
Supervised by Dr Christopher Rowlands at Imperial College London, Ze Lum built a test system that mimics a real human eye, to automatically take full diagnostic maps of the retina, to help replace experiments on cats and monkeys.
Supervised by Dr Zaynah Maherally at the University of Portsmouth, Thomas Clark unlocked the role of pericytes (cells that line blood vessels) in an all-human blood-brain barrier model, to help replace rats and mice in brain tumour research.
Supervised by Dr Nathaniel Milton at Leeds Beckett University, Sheree Smith researched the replacement of antibodies with non-animal synthetics (nucleotide aptamers) for use in Alzheimer’s disease and cancer research, to help replace experiments on mice.
Supervised by Dr Nick Peake at Sheffield Hallam University, Rachel Sharp built a physiologically relevant model of fat development during inflammatory bowel disease, to replace experiments on mice.
Supervised by Dr Adrian Biddle at Queen Mary University London, Olivia Knowles identified a novel cancer stem cell sub-population in melanoma (skin cancer) samples using a new protocol, to help replace the use of mice.
Supervised by Michelle Botha at the University of Hertfordshire, Niamh Haslett developed computer models to predict psychoactivity in new drugs rather than testing in mice.
Supervised by Dr Helen Colley at the University of Sheffield, Jowi Guillen developed tissue-engineered models to study the development of oral cancer, to help replace experiments on mice and hamsters.
Supervised by Dr Paul Roach at Loughborough University, Jodie Evans developed microfluidic neuronal cell circuits from computer-aided design through to 3D printing to help replace tests on mice and monkeys.
Supervised by Dr Susan Scholes at Newcastle University, Georgia Ellis developed a pea-protein lubricant to help replace foetal calf serum for the wear testing of artificial joints.
Supervised by Dr Sylwia Ammoun at Plymouth University, Foram Dave used a human cell culture model to study cells from brain tumour patients and test drugs, allowing a faster ‘bench to bedside’ transition into clinical trials without animal tests.
Supervised by Professor Nikolai Zhelev at Abertay University, Emma Ewen reviewed hypertrophic cardiomyopathy (thickening of the heart muscle) research to show that human organoid cultures are more relevant than experiments on beagles.
Supervised by Dr Ewelina Hoffman at the University of Hertfordshire, Elisa Ali developed a human in vitro model to help replace rats and mice in pulmonary (lung) fibrosis research.
Supervised by Dr Leonid Nikitenko at Hull University, Eamon Faulkner developed fully humanised and animal free models to study the role of blood vessel cells in chronic diseases.
Supervised by Dr Matthew Kitching at Durham University, Domonkos Perenyi used artificial cell mimics to replace the use of egg yolk in understanding how cell membranes move.
Summer Student Nefisa Marium undertook a project to monitor vitamin D metabolism using human cell culture, rather than using mice. Her work will enable researchers worldwide to gain greater understanding of how vitamin D is truly handled in human health and disease.
Baransel Kamaz undertook a Summer Studentship in 2014 to directly study human liver cancer using human-derived cells, under the supervision of Dr. Meritxell Huch at the University of Cambridge. They hope that the results will replace experiments on rats and mice.
Alexander Lanz, at the University of Sheffield, developed a cell culture model of osteoarthritis, to replace current experiments on guinea pigs, rats and rabbits.
Diliany Oliveira, supervised by Dr Mridula Chopra at the University of Portsmouth, developed a non-animal based screening tool to detect cancer biomarkers and replace the use of animals in prostate cancer research.
Emma-Jane Macrae, supervised by Professor Graeme Houston at the University of Dundee, helped develop a clot model that could be used to train doctors in treating strokes, to replace experiments on pigs.
Joanitta Akpai from the University of Hertfordshire will be working on developing novel biomaterials from pasta to create 3D cell culture models to help to replace the use of rodents in vascular disease and cancer research.
Joy Girgis at the University of Hertfordshire used human cell culture to develop novel testing methods in lung disease studies to replace rats.
Lauren Richardson, supervised by Dr Luigi De Girolamo at Nottingham Trent University, studied the proteins related to Parkinson’s disease, to replacing experiments on primates, rats and mice.
Supervised by Dr Colin Boyle at Imperial College London, Sergi Fayos Villalta undertook a computational modelling project looking at the development of pressure ulcers and soft tissue damage to replace the use of mice and rats.
Stephanie Lunt, supervised by Dr Adrian Biddle at the Animal Replacement Centre Queen Mary University of London, used patient cancer samples to identify biomarkers in skin cancer to help replace the use of mice.
Bronte Munro, supervised by Dr Jelena Gavrilovic at the University of East Anglia, investigated the causes of atopic dermatitis and psoriasis using cell culture, to replace experiments on mice.
Edward Nendick, supervised by Dr Mandy Johnstone at the University of Edinburgh, used one of the latest cutting-edge gene editing technologies, CRISPR-Cas9, to further our understanding of schizophrenia and replace experiments on mice.
Evie Gruszyk, supervised by Dr Nicholas Peake at Sheffield Hallam University, developed a cell culture model to understand colorectal cancer without experimenting on mice.
Oana Voloaca, supervised by Dr Melissa Lacey at Sheffield Hallam University, used a novel gut tissue model to investigate the influence of bacteria in gastrointestinal diseases (such as crohn’s disease), to replace experiments on rats.
Rachel Henderson, supervised by Dr Helen Wheadon at the University of Glasgow, used human-relevant research to study leukaemia without using animals.
Shreya Asher will be working at Queen Mary University of London on a skin cell culture model to better understand skin cancer without having to conduct any experiments on mice.
Taleen Shakouri, supervised by Dr Stewart Kirton and Dr Michelle Botha at the University of Hertfordshire, developed a toxicology computer model, to replace experiments on monkeys, dogs and mice.
Page last modified on January 29, 2019 11:44 am