Summer Student 2017: Edward Nendick

Edward Nendick, supervised by Dr Mandy Johnstone at the University of Edinburgh, used one of the latest cutting-edge gene editing technologies, CRISPR-Cas9, to further our understanding of schizophrenia and replace experiments on mice.

Schizophrenia is a common devastating condition and while partially effective treatments are available, none are disease-modifying. There is a need for novel models of mental illness in human-derived cells to develop more effective therapies.

Edward used stem cells from individuals with and without disease-associated genetic mutations to investigate how disease risk is conferred at a cellular level. His research could lead to a way to correct the disease-associated mutation in the patients and thereby find a better way to treat and cure patients with schizophrenia.

Page last modified on June 13, 2019 12:20 pm